There quite frankly many, many arguments for why the War on Drugs ought to end immediately. One such reason that I think is not discussed enough is the fact that it is Unconstitutional. To justify this claim we merely need to go to look at the 1st and 14th amendment. The most obvious way this violation occurs is with religious freedom. The fact of the matter is that many of the drugs that have been most affected by the War on Drugs, including the most affected Cannabis are legitimate sacraments for various faiths.
One fact that must be kept in mind when talking about which religions are being violated by the War on Drugs is that with perhaps exception to the Church of Cannabis most (if not all) religions affected by the War on Drugs are religions that have roots in cultures that aren’t white. For example, the most famous use of Cannabis for religious purposes is Rastafarian faith. You only need to do a mere Google search and 10 minutes of research to understand that this faith is very… well Afro-centric. This isn’t even the only faith to use cannabis as a sacrament. Cannabis is also highly regarded in Hinduism as a sacrament to worship Shiva. In Buddhism, some sects have been known to use it to help mediate. Mind you these examples are merely talking about cannabis. Many more faiths use some form of psychedelics (mostly of course being religions mostly of people of color) as a sacrament.
The argument can really be boiled down to this simple line of logic. The 1st amendment protects the right to practice whatever faith you please and the 14th amendment gives equal protection for every citizen under the law. Any sort of law that both denies people the means of practicing their religion, for example not allowing them to use a holy sacrament violates the 1st amendment. Any law that results in unequal application of the law, for example being a law that statistically and historically can be shown to be racist, is a violation of the 14th amendment. So you can like the War on Drugs or you can respect equal protection under the law/freedom of religion but you cannot do both without being completely hypocritical to everything those two amendments stand for.